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Enhance MD (Enhance.MD LLC) is a San Diego-based telehealth metabolic wellness platform offering compounded GLP-1 medications, NAD+ therapy, and men's health services. The company positions itself as more than a simple GLP-1 prescription service by focusing on overall metabolic health. Their standout feature is the same-price-at-every-dose guarantee, meaning your monthly rate stays flat whether you are on a starting dose or have titrated up to the maximum. The program includes comprehensive metabolic lab testing at intake and every 6 months (conducted at Quest Diagnostics), wellness coaching, and ongoing provider consultations.
The flat-rate pricing model across all dose levels remains a genuine differentiator — many competitors charge significantly more at higher doses, so Enhance MD's approach provides cost predictability throughout treatment. The mandatory lab testing before starting medication and at regular intervals (comprehensive metabolic panel, TSH, lipids, and HbA1c at Quest Diagnostics) shows a commitment to patient safety that exceeds many telehealth competitors. The tiered product lineup now offers more flexibility than before, with the newer Microdosing Tirzepatide option at $169/month providing an affordable entry point for patients seeking lower-dose metabolic support rather than aggressive weight loss.
The minimum BMI requirement of 25 excludes some patients who might benefit from treatment. The onboarding process can be slower than competitors due to the mandatory lab testing requirement, which some patients find inconvenient despite it being a safety feature. A few reviewers report that the initial intake call felt rushed or impersonal. Some negative reviews cite shipping delays and communication gaps during the medication fulfillment process. The company does not accept FSA/HSA payments, which is a limitation for patients hoping to use tax-advantaged health accounts.
Enhance MD is a solid choice for patients who value medical oversight, predictable pricing, and a holistic approach to metabolic health. The flat-rate dosing model and included lab testing set it apart from bare-bones prescription services. Best for patients who want comprehensive care with built-in safety monitoring and are willing to invest in a more thorough onboarding process. The annual prepay option offers meaningful savings for those ready to commit.
Compounded semaglutide is $249/month on a monthly plan or $212/month with annual prepay. Compounded tirzepatide is $329/month or $280/month with annual prepay. GLP-1 Elite (semaglutide + tirzepatide combo): $322/month on the annual plan (first month $222). Microdosing Tirzepatide (1mg/week): $169/month. All GLP-1 prices include provider consultations, medication, lab testing every 6 months, syringes, alcohol pads, wellness coaching, free shipping, and platform access. Current promotion: $50 off 1-month plans or $100 off multi-month plans, no code required. FSA/HSA payments are not accepted.
Yes, Enhance MD requires comprehensive metabolic lab testing before starting medication and every 6 months during treatment. Labs include a comprehensive metabolic panel (CMP), thyroid-stimulating hormone (TSH), lipid panel, and hemoglobin A1c (HbA1c). Testing is conducted at Quest Diagnostics locations and is included in your subscription cost at no additional charge. Follow-up provider visits are required every 90 days.
Enhance MD prescribes compounded semaglutide (GLP-1 Core), compounded tirzepatide (GLP-1 Advanced), a semaglutide + tirzepatide combination (GLP-1 Elite), and low-dose tirzepatide for microdosing. NAD+ therapy is available as injections or oral wafers. Medications are prepared by partner compounding pharmacies including Strive Pharmacy, TruMedRx, and The Pharmacy Hub. These are compounded medications not FDA-approved for safety or effectiveness. The company does not offer brand-name GLP-1s like Wegovy or Zepbound. Enhance.MD also offers testosterone replacement therapy (TRT) as part of its men's health services.
Unlike many GLP-1 telehealth providers that increase prices as your dosage increases during treatment, Enhance MD charges the same monthly rate regardless of your dose level. Whether you are on a starting dose or have titrated up to the maximum therapeutic dose, your monthly cost remains the same within your chosen tier. The company states: "the price you see for any medication is the price you'll pay, every time, regardless of dosage."
You start by completing a medical intake form online, which includes your health history and BMI calculation (minimum BMI of 25 required). After submitting payment, Enhance.MD arranges blood work at a nearby Quest Diagnostics lab (comprehensive metabolic panel, TSH, lipids, HbA1c). Once results are received, you have a virtual consultation with a licensed medical provider from Enhance Wellness PC or iThriveMD PC. If prescribed, medication ships to your door from one of Enhance.MD's partner compounding pharmacies. Follow-up provider visits are required every 90 days. If found ineligible during onboarding, a 100% money-back guarantee applies.
