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Gentle Patches (gentlepatches.com) is NOT a telehealth provider and does NOT sell prescription GLP-1 medications. It is a Lithuania-based direct-to-consumer wellness brand selling over-the-counter dietary supplement patches — originally marketed as "GLP-1 Patches" and now rebranded as "Berberine Patches (Formerly GLP-1)" with the same unchanged formula. Despite the GLP-1 branding still used on active affiliate landing pages, these patches do not contain semaglutide, tirzepatide, or any actual GLP-1 receptor agonist. The active ingredients are herbal supplements including berberine, cinnamon extract, green tea extract, B vitamins, L-glutamine, and chromium.
Rather than prescription GLP-1 medications, Gentle Patches contain a blend of dietary supplements delivered through a transdermal patch: berberine extract (a plant compound with some blood sugar effects), cinnamon extract (for blood sugar and insulin sensitivity support), green tea extract/EGCG (a source of caffeine and antioxidants), a Vitamin B Complex including B1, B2, B3, B5, B6, and B12 (for metabolism and energy), L-glutamine (an amino acid for muscle recovery), and chromium (a mineral for glucose metabolism). While some of these individual ingredients have limited evidence for modest metabolic effects when taken orally, none of them function as GLP-1 receptor agonists.
Gentle Patches is registered at Švitrigailos g. 34, LT-03230, Vilnius, Lithuania. The company identifies itself as "founded by health entrepreneurs passionate about longevity and modern wellness" but does not name any founders, medical advisors, or formulators. It sells through its own Shopify store, Amazon, and aggressive affiliate marketing funnels. The brand ships from US and EU warehouses, with delivery times of 5–7 days domestically and 7–14 days internationally. Beyond the GLP-1/Berberine patch, Gentle Patches also sells NAD+, Collagen, and Dopamine patches — none of which are prescription-based.
Gentle Patches are supplement products, not medical treatments, and should not be confused with prescription GLP-1 medications. The product contains no GLP-1 drugs, has never been clinically tested as a formula, has no FDA approval, and is sold by an anonymous Lithuania-based company with a very low trust score and mixed consumer reviews. The marketing makes extraordinary weight loss claims without clinical evidence, uses misleading GLP-1 branding on affiliate pages even after officially rebranding, displays unverified media endorsement logos, and has generated significant consumer complaints around unauthorized charges, non-delivery, and refund difficulties. If you are considering GLP-1 therapy for weight loss, consult with a licensed healthcare provider about prescription options like semaglutide or tirzepatide. Over-the-counter patches marketed with GLP-1 branding are not a substitute for medically supervised weight loss treatment.
No. Despite the GLP-1 branding still used on affiliate landing pages, Gentle Patches do not contain semaglutide, tirzepatide, or any prescription GLP-1 receptor agonist. They contain herbal supplements including berberine extract, cinnamon extract, green tea extract, B vitamins, L-glutamine, and chromium. The company has renamed the product to "Berberine Patches (Formerly GLP-1)" with no formula change. The FDA has stated directly that "there are no FDA-approved GLP-1 patches." Actual GLP-1 molecules are too large to be absorbed through the skin, and there is zero published research on transdermal delivery of berberine.
No. Gentle Patches are sold as dietary supplements, not medications, and are not FDA-approved for weight loss or any medical condition. The product is described as "FDA-registered," but FDA registration is merely a facility listing — it does not mean FDA approval for safety or effectiveness. Only prescription GLP-1 medications like Wegovy (semaglutide) and Zepbound (tirzepatide) have FDA approval for weight management. There are also no FDA-approved drug products containing berberine.
GLP-1 supplement patches typically cost between $25 and $60 per month, depending on the brand and retailer. While significantly cheaper than prescription GLP-1 medications, they contain completely different ingredients and have no clinical evidence demonstrating comparable weight loss results.
A single 30-day supply (30 patches) is $34.99, though the website shows an inflated crossed-out "retail price" of $116.63. The best deal bundle (Buy 3, Get 2 Free) provides a 150-day supply for approximately $105, or about $21 per month, and includes free bonus NAD+ and Dopamine patches plus a mystery gift. Various landing pages advertise 59–70% discounts. A 30-day money-back guarantee is advertised, but multiple reviewers report difficulty obtaining refunds, particularly for international returns.
Medical professionals and named experts widely advise against GLP-1 patches as a weight loss solution. C. Michael White (University of Connecticut) states that oral berberine produces only 2–4 pounds of weight loss and that there is zero research on transdermal delivery. Jamie Alan (Michigan State) states: "If you can buy it without a prescription, it's not an actual GLP-1 drug." The FDA has confirmed there are no approved GLP-1 patches. NBC News/TODAY.com, Baptist Health, Ro, Noom, and NutritionNC have all published warnings that these products misleadingly capitalize on the GLP-1 brand name while delivering unproven herbal supplements. Consumer reports of skin rashes, burns, and blisters have also been documented.
